It is forbidden to vaccinate clinically sick and/or weakened birds.Birds at the age of 90–120 days are subject to vaccination, but not later than 1 monthprior to the beginning of the egg-laying. The vaccine is admini stered once in the volume of 0,5 cm3hypodermically into a middle third of a neck or intramuscularly in area of a pectoral muscle with observance of rules of an asepsis.
The revaccination of hens of parental herds more senior than 7 months is allowed according to indications. Before use the vaccine is maintained by 3–4 hours at a temperature from +18 to +20°C. Beforeapplication and during immunization the vials with a vaccine periodically is stirred up for restoration of uniformity of an emulsion. For vaccination there are used syringes (machine guns, semiautomatic devices) which will are sterilized by boiling within 20 minutes. Use of disposable syringes is allowed.